A thorough genetic NGS panel for congenital neutropenia, including the following genes was performed by DNA target sequence enrichment capture with Miseq illumine analysis, being all unmutated: AK2, AP3B1, BLOC1S3, CDAN1, CLPB, COH1/VPS13B, CSF3R, CXCR4, DTNBP1/BLOC1S8, DYN2/DNM2, EIF2AK3/PERK, ELANE/ELA2, G6PT1/SLC37A4, G6PC3, GATA-1, GFI1, HAX1, HPS1, HPS3, HPS4, HPS5, HPS6, JAGN1, LYST, MAPBPIP/LAMTOR2, MYO5A, PLDN/BLOC1S6, RAB27A, RMRP/CHH/NME1, SEC23B, SLC19A2, SLC25A38, SLC37A4, SMARCAL1, TAZ, TCIRG1, USB1, VPS13B, VPS45, WAS/SCNX. Here, EIF2AK3 is linked to severe congenital neutropenia.