Despite this, the activation and function of memory‐derived 2° effector OT‐I cells in the spleen and brain during secondary PbA‐OVA infection was comparable to 1° effector OT‐I cells during a primary infection, with memory‐derived 2° effector OT‐I cells and 1° effector OT‐I cells exhibiting very high levels of GrB (Figure 4h,i). Here, GZMB is linked to infection.