CD8A and infection: However, in agreement with other studies showing that repetitive antigen stimulation can induce stepwise changes in the memory CD8+ T‐cell compartment [52, 53, 63], we observed a slight increase in the proportion of Tem OT‐I cells and a small decrease in the frequencies of TdTe KLRG‐1+ OT‐I cells (i.e. long‐lived effector T cells) following three rounds of PbA‐OVA infections.