In the RZV group, median CD4[2+] T-cell frequencies ranged between 18.3 (in NHBCL patients; interquartile range: 1.0–48.9) and 408.6 (1.0–816.3) at pre-vaccination, were highest at 1 M post-dose two across underlying diseases (3294.2 [in NHBCL patients; 2040.4–11857.2] to 21359.7 [19334.4–23385.1]), and ranged between 1691.0 (in MM patients; 579.5–3862.9) and 16573.2 (16573.2–16573.2) at 24 M post-dose two. This evidence concerns the gene CD4 and Miyoshi myopathy.