Moreover, lnc-ITSN1-2 may promote the differentiation of T helper type 1 (Th1) and Th17 cells in CD4+ T cells of inflammatory bowel disease (IBD) via regulating the microRNA (miR)-125a/interleukin (IL)-23R axis (Nie and Zhao 2020). The gene discussed is CD4; the disease is inflammatory bowel disease.