Cytokines are essential to infection control, but when the immune system is deregulated including the imbalanced response of type 1 and type 2 T helper cells, a cytokine storm will be observed, resulting in an excessively elevated level of cytokines, such as C‐reactive protein interleukin 8 (IL‐8), IL‐10, procalcitonin, IL‐1b, and tumor necrosis factor‐α particularly IL‐6 coupled with tissue damage and multiple organ dysfunctions.92 The gene discussed is IL1B; the disease is infection.