ANXA5 and neoplasm: Recently, it has been demonstrated in mice that anxA5 countered immunosuppression induced by chemotherapy in peritumoral tissues, enhanced general anti-tumor efficacy and thus could, in combination with cisplatin and a human papillomavirus 16 (HPV-16)-derived E7 peptide, reverse HPV-16-positive cervical tumor growth and let the mice survive [32].