ALB and amyotrophic lateral sclerosis: However, except for a higher proportion of ALS patients with blood/CSF barrier dysfunction compared with dementia (14.8%, P = 0.016), those parameters did not differ between ALS, dementia (total protein 453 mg/l, IQR 360–597, p = 0.999; albumin quotient 5.4, IQR 4.1–7.2, P = 0.241), and PPMS (total protein 461 mg/l, IQR 360–583, P = 0.999; albumin quotient 5.7, IQR 4.0–8.0, P = 0.999; blood/CSF barrier dysfunction 18.2%, P = 0.999) patients.