,22 In detail, we showed an increase of CD14+CD16+ monocytes in the PB of ALS patients, as described by Murdock et al.5However, in contrast to the mentioned study, our data further described a decrease in CD14+CD16− monocyte levels compared with CLTR, which is consistent with an earlier study of the same research group and other investigations.22 Here, CD14 is linked to amyotrophic lateral sclerosis.