Our results showed for the first time that the expression levels of RhoF in CD8+ T cells (GSE14924), CD34+ or CD34- bone marrow cells (GSE30029, TCGA) and peripheral blood mononuclear cells (PBMCs) (GSE65409) in AML patients were obviously higher than those in their normal counterparts. The gene discussed is CD8A; the disease is acute myeloid leukemia.