Our results showed for the first time that the expression levels of RhoF in CD8+ T cells (GSE14924), CD34+ or CD34- bone marrow cells (GSE30029, TCGA) and peripheral blood mononuclear cells (PBMCs) (GSE65409) in AML patients were obviously higher than those in their normal counterparts. Here, RHOF is linked to acute myeloid leukemia.