Next, to determine the mRNA expression features of RhoF and RhoD in non-M3 AML patients, the RhoF and RhoD expression levels in TCGA datasets (Acute Myeloid Leukemia, NEJM 2013, n=157) 24 were compared, revealing a high RhoF expression level over that of RhoD (Figure 3A). Here, RHOD is linked to acute myeloid leukemia.