Second, this was a preliminary exploration of the distribution of gene expression based on clinical cross-sections with small sample sizes, and present can only aid in drawing the possible correlations between SLC34A2 and SLC4A4 with invasion, metastasis, and excess iodine intake of PTCs; subsequent efforts should involve in a series of in vivo and in vitro gain- or loss-of-function experimental assays (K1 and TPC-1, and xenograft tumor in nude mice) 44 to reveal the upstream and downstream and further explore deeper mechanisms. Here, SLC4A4 is linked to neoplasm.