CSF and blood cultures confirmed beta-lactamase-negative ampicillin-resistant (BLNAR) Haemophilus influenzae type b meningitis susceptible to ceftriaxone, meropenem, and cefotaxime, so it was decided to continue with intravenous ceftriaxone (200 mg/kg/day) and dexamethasone. The gene discussed is LACTB; the disease is infectious meningitis.