Furthermore, in the HBsAg-positive DLBCL group, though there was no significant statistical difference in complete response between the R-CHOP and CHOP groups, complete response in the R-CHOP group was better than that in the CHOP group with a higher rate of complete response (70.0% vs. 54.5%, P = 0.082, Table 3). The gene discussed is DDIT3; the disease is diffuse large B-cell lymphoma.