Furthermore, DLBCL in the HBsAg-positive group showed more frequent involvement of the spleen (19.7% vs. 6.1%, P < 0.001), more advanced disease (stage III/IV: 56.7% vs. 45.1%, P = 0.028), less frequent involvement of the small and large intestine (2.3% vs. 11.2%, P = 0.003), and lower expression rate of MYC (49.1% vs. 66.7%, P = 0.026). The gene discussed is MYC; the disease is diffuse large B-cell lymphoma.