This analysis was performed on two data sets: five human adrenocortical carcinoma samples profiled for H3K27ac (unpublished data) and the erythroleukemic murine cell line, with doxycycline inducible shRNA against Spi1, further called shSpi1-A2B profiled for H3K27ac in two conditions: (1) with Spi1-overexpressed: Spi1++, and (2) Spi1-repressed: Spi1− [17]. Here, SPI1 is linked to adrenal cortex carcinoma.