Wang NY et al7 evaluated prognostic values of these same three tumor biomarkers with HCC patients after radiofrequency ablation, and their results demonstrated that the short‐term (6 months) recurrence rate of AFP‐positive patients was obviously higher than that of AFP‐negative patients, but AFP‐L3 and GP73 levels were not associated with short‐term recurrence. This evidence concerns the gene AFP and hepatocellular carcinoma.