MitoQ, a mitochondria-specific antioxidant known to improve mitophagy in a PINK1-dependent manner (68), significantly attenuated the severity of LCWE-induced KD vasculitis and significantly reduced tissue ROS production and systemic 8-OHdG release, suggesting that targeting mitophagy might be beneficial to treat IL-1β driven vasculitis. This evidence concerns the gene IL1B and vasculitis.