HOTAIR and head and neck squamous cell carcinoma: For example, LncRNA UCA1 promotes the proliferation of HNSCC and cisplatin resistance through inhibiting the expression of miR-184 [11]; lncRNA EGFR-AS1 mediates epidermal growth factor receptor to regulate therapeutic response of HNSCC [12]; STAT3/HOTAIR signal regulates the growth of HNSCC in an EZH2-dependent manner [13].