TGFB1 and intervertebral disk degenerative disorder: In addition, the KEGG Pathway enrichment analysis of LmiRM-Degenerated showed that these LmiRM-Degenerateds were related to TGF-Beta signaling pathway, Th17 cell differentiation, and Human T-cell leukemia virus 1 infection, indicating that the occurrence of IDD was a complicated process associated with TGF-beta and immune processes.