TNF and metabolic dysfunction-associated steatotic liver disease: The fat distribution also plays an important role in the development of NAFLD, visceral obesity measured by waist circumference and waist/hip ratio has a hepatotoxic effect through a release of several inflammatory markers, such as tumor necrosis factor (TNF) and interleukin-6 (IL-6), in addition to fatty acid accumulation in the liver parenchyma [26].