Trx‐1‐transgenic (Trx‐1 Tg)/C57BL/6 mice, in which hTrx‐1 is systemically overexpressed under the control of the β‐actin promoter, are more resistant to acute pancreatitis (Ohashi et al., 2006) and diabetes (Hamada et al., 2009; Hotta et al., 1998; Yamamoto et al., 2008). The gene discussed is TXN; the disease is acute pancreatitis.