In this context, our study displayed the association of cytokines in MNCs (including HSCs and MSCs) involved in the interplay at the diagnostic time of myeloid malignancy, especially presenting the association of NGAL with the relatively well known cytokine genes such as STAT3, TLR4, IL5, TLR1 and TLR2. This evidence concerns the gene TLR4 and myeloid neoplasm.