Moreover, a positive correlation exists between the PD-L1 expression level and infiltrating levels of B cell (r = 0.282, P = 1.87e-03), CD8+ T cells (r = 0.551, P = 5.54E-15), Macrophages (r = 0.583, P = 5.62E-17), Neutrophils (r =0.597, P = 6.45E-18), and DCs (r = 0.670, P = 1.26E-23) in pancreatic cancer (Figure 5). This evidence concerns the gene CD274 and familial pancreatic carcinoma.