Consistent with our findings, former research reported that both mRNA and protein level of UHRF2 were upregulated in intrahepatic cholangiocarcinoma tissues and the overall survival rate of intrahepatic cholangiocarcinoma patients with low UHRF2 level was obviously higher than those with high UHRF2 level 33. The gene discussed is UHRF2; the disease is intrahepatic cholangiocarcinoma.