The results showed that an increased proportion of IFN-γ secreting T cells (CD8+ and CD4+ T cells) and a significantly decreased proportion of CD4+CD25+foxp3+ regulatory T cells were observed in abscopal tumours with mice treated with LIA+L (Fig. 6g, j and Supplementary Fig. 21b, d, e). The gene discussed is CD4; the disease is neoplasm.