JUN and neoplasm: FOSL1, which encodes FRA-1, is an AP-1 transcription factor (TF) with prognostic value in different epithelial tumors, where its overexpression correlates with tumor progression or worse patient survival (Chiappetta et al., 2007; Gao et al., 2017; Usui et al., 2012; Vallejo et al., 2017; Wu et al., 2015; Xu et al., 2017).