FGF23 and cardiovascular disorder: It has been intensely understood that autophagy functions in the cardiovascular diseases [13, 14], and the autophagic phenotype associated to vascular smooth muscle linking to steogenic differentiation [15], apoptosis [16], inflammation [17], Fibroblast Growth Factor 23 (FGF23)-Klotho [17, 18], Matrix Vesicle (MV) release [19], and oxidative stress [20] physiological or pathological conditions.