In a genetic study on 64 Egyptian patients, 40 with hypertension and 24 with type 2 diabetes, the D allele of ACE gene was associated with increased risk of hypertension and/or diabetes than DI allele (OR = 3.00; 95%Cl 0.993–9.067) and II allele (OR = 4.250; 95%CI 1.234–14.630a) than healthy controls [85]. Here, ACE is linked to type 2 diabetes mellitus.