IFIH1 and infection: For example, the HSV protein ICP34.5 (a.k.a. γ134.5) recruits PP1 via an RVxF motif to promote dephosphorylation of eIF2α, thereby alleviating the translational blockade promoted by the infection-stimulated protein kinase R [66,67], measles virus V protein sequesters PP1 via an RVxF-like motif to prevent MDA5 dephosphorylation [68], and recruitment of PP1 via an RvXF-like motif by the HIV Tat protein promotes HIV transcription [69].