In all cancer types except uveal melanoma, the EMT and TGF-β signaling pathway activities were higher in stromal cells than in tumor cells (Figure 6), and their activities were the highest in cancer-associated fibroblasts (C10_COMP and C11_SERPINE1 fibroblasts), consistent with the observations of Qian et al.12. The gene discussed is TGFB1; the disease is neoplasm.