Recent in vivo studies have confirmed the regional co-localization of inflammation and 18F-AV-1451 binding in PSP, including in many cortical areas,65 in line with previous in vivo66,67 and post-mortem68 reports of the tight interplay between neuroinflammation and tau accumulation in tauopathies. The gene discussed is MAPT; the disease is supranuclear palsy, progressive, 1.