CRP and congenital rubella syndrome: This dysregulated immune response also known as cytokine release syndrome (CRS) or cytokine storm is characterized by elevation in systemic inflammatory markers (C-reactive protein (CRP), ferritin, lactate dehydrogenase (LDH) and D-dimer) and aberrant pro-inflammatory cytokine secretion (IL-6, soluble IL-2 receptor [IL-2R], IL-10, TNF-α) by pulmonary alveolar macrophages.