PRTN3 and endocarditis: Subsequently, the inflammatory response decreased steadily, and renal function, the urinary findings and the levels of PR3-ANCA improved [CRP: 2.09 mg/dL, eGFR: 40.4 ml/min.1.78 m2, proteinuria 2.32 g/gCr, PR3-ANCA: 9.7 IU/mL] on hospital day 30 with antibiotic therapy for management of the endocarditis (Fig. 2).