In addition, increased levels of cTnI, lactate dehydrogenase, and lymphocytopenia were more common in patients with severe COVID-19.[13] Also, studies have shown that SARS-CoV-2 can participate in and induce the activation of the complement and coagulation system, which is related to the severity of COVID-19 patients.[14] Myocardial injury was another independent risk factor for deterioration and death in patients with COVID-19. The gene discussed is TNNI3; the disease is COVID-19.