CCNF and cancer: The cBioPortal for Cancer Genomics website (www.cbioportal.org) lists diverse cancers in which CCNF alterations (mutations, amplifications, or deletions) have been identified.[16] We found that alterations in CCNF had potential great impacts on the occurrence and development of some tumors, such as adrenocortical carcinoma and melanoma (Fig. 6A).