The abnormal expression of CCNF is related to various forms of cancer and certain neurological diseases, such as amyotrophic lateral sclerosis, frontotemporal dementia.[10] In this study, we employed multiple bioinformatics analysis methods to inquire CCNF expression and elucidate the significance of abnormal CCNF expression in hepatocellular carcinoma (HCC) and its potential value for prognosis and diagnosis. The gene discussed is CCNF; the disease is frontotemporal dementia.