However, a similar relationship was not observed between HHLA2 expression and gender (OR = 1.21, 95% CI: 0.91–1.61), tumor size (OR = 1.28, 95% CI: 0.86–1.90), clinical stage (OR = 1.68, 95% CI: 0.94–3.00), tumor depth (OR = 1.67, 95% CI: 0.78–3.59) and distant metastasis (OR = 1.52, 95% CI: 0.83–2.79). Here, HHLA2 is linked to neoplasm.