TNF and COVID-19: As pharmaceutical therapies, Forsythia has many effects in inhibiting a variety of viruses, including influenza A virus, human cytomegalovirus, encephalitis B virus, and respiratory syncytial virus.[31] Another Chinese medicine, Xue-bi-jing injection, can improve hemodynamics, reduce the levels of inflammatory factors such as TNF-a, inhibit excessive inflammatory response, and mitigate myocardial damage caused by sepsis.[32] Thus, the utilization of TCM in managing COVID-19 is substantial.