We set up Western blot protocols for six of the most strongly regulated CPA proteins belonging to ALS-relevant molecular pathways: Glypican-4 (GPC4), Fibromodulin (FMOD), Biglycan (BGN), Cation-dependent mannose-6-phosphate receptor (M6PR), Endophilin-B2 (SH3GLB2) and Protein DJ-1 (PARK7). This evidence concerns the gene SH3GLB2 and amyotrophic lateral sclerosis.