IRF5 and neoplasm: As expected, the CD163 expression was positively correlated with most of gene markers of these tumor-infiltrating immune cells in both the TCGA and CGGA cohorts, including CD8A, CD8B, CD3D, CD3E, CD2, CD79A, CD86, CSF1R, CCL2, CD68, IL10, IRF5, COX2, VSIG4, MS4A4A, ITGAM, CCR7, KIR2DL4, HLA-DPB1, HLA-DQB1, HLA-DRA, HLA-DPA1, CD1C, NRP1, ITGAX, GATA3, STAT6, STAT5A, BCL6, STAT3, FOXP3, PDCD1, CTLA4, HAVCR2, and GZMB (Table 2).