Plasma BNP evidenced the best discriminatory ability for the prediction of ischemia compared to all evaluated biomarkers and demonstrated statistically higher AUC [0.837 (95% CI = 0.729–0.946, p < 0.001)] compared to those of the following biomarkers: sST2 (DeLong test: p = 0.042), syndecan-1 (DeLong test: p = 0.022), and cystatin C (DeLong test: p = 0.022). The gene discussed is CST3; the disease is ischemia.