COL1A1 and cancer: COL1A1 is known to be overexpressed in several cancers other than gastrointestinal cancers (Shi et al., 2015; Zhang et al., 2018; Yin et al., 2019), such as thyroid cancer (Huang et al., 2019), lung cancer (Grigoroiu et al., 2015), breast cancer (Liu et al., 2018b), and renal cancer (Boguslawska et al., 2016).