MS4A1 and neoplasm: Combined with the overall analysis of TMB and TIME, we found that the higher TMB in OC, the more cytokines and chemokines in TIME, the higher the level of tumor immune infiltration, and we also identified a set of genes in OC that were related to OC immunotherapy and good prognosis, such as CXCL13, FCRLA, PLA2G2D and MS4A1 (Figure 8).