RB1 and small cell lung carcinoma: Functional annotation showed that a higher proportion of biological processes or pathways were shared in common between SCEC and SCLC and were associated with the cell cycle, mitosis, DNA replication, telomere maintenance, DNA repair, and p53 and RB pathways (count ≥10 and Benjamini p-value < 0.05; Table 2 and Supplementary Tables 2–4).