The SNP rs12537 present in the miR-181a-binding site in the 3' UTR of the MTMR3 gene (15) and T/C variant in MTMR3 were reported to be associated with IgA nephropathy, RA, SLE and gastric cancer (13–16). The gene discussed is MTMR3; the disease is systemic lupus erythematosus.