In the same line, octogenarians with a MEC score < 24 (n = 47), indicating cognitive impairment, showed higher concentrations of platelet-derived total and AV+ CD36+/GPVI+ and GPVI+/AV+ cMV; and CD9+/AV– and CD36+/AV– cMV compared to subjects with MEC scores ≥ 24 (n = 88), as depicted in Supplementary Figure 6 (P ≤ 0.034, all). Here, GP6 is linked to Cognitive impairment.