CYCS and hepatocellular carcinoma: Recently, NF-κB inhibition was found with tumor-suppressive effect in HCC (Tsang et al., 2016) and the NF-κB inhibitor (Bay11-7082) was observed to reduce cell viability, increase ROS formation, release cytochrome c, and induce apoptosis in HepG2 cells (Ahmadian et al., 2018).