In ovarian cancer, CADM1 overexpression upregulates genes like LXR/RXR, IGF1, IFI44L, and C4BPA, in addition to inhibiting the PI3K/Akt/mTOR pathway as well as affecting the downstream (APP, EDN1, TGFBI, and Rap1A) expression (Si et al., 2020). This evidence concerns the gene CADM1 and ovarian carcinoma.