Similarly, in diseases, such as Kaposi’s sarcoma (KS) and primary exudative lymphoma (PEL) caused by Kaposi’s sarcoma herpes virus/human herpes virus 8 (KSHV/HHV8), CADM1 is possibly involved in chronic NF-κB activation (Hunte et al., 2018). This evidence concerns the gene CADM1 and Kaposi's sarcoma.