CADM1, also known as TSLC1, IGSF4, SgIGSF, and SynCAM (Kuramochi et al., 2001; Watabe et al., 2003), belongs to the immunoglobulin superfamily and was initially identified as a tumor regulator in small cell lung cancer (SCLC). This evidence concerns the gene CADM1 and small cell lung carcinoma.