The latter was supported by the fact, that abundant FSTL3 expression is obviously related to the expression of EMT-related genes, including E-cadherin (CDH1), N-cadherin (CDH2), Fibronectin-1 (FN-1), and Vimentin (VIM) in CRC tissues, illustrated by the GEPIA database (see footnote 2) (Supplementary Figure 3). Here, CDH1 is linked to colorectal carcinoma.