PD-L1 was expressed in ≥ 1% of TCs in 69% of patients, in ≥ 50% of TCs in 12% of patients, and ≥ 5% of either TCs or infiltrating immune cells in 71% of patients.CD8+ TILs were present in tumors from all patients.High CD8+ TILs levels in NPC were associated with a longer OS. This evidence concerns the gene CD274 and nasopharyngeal carcinoma.