Lipophosphoglycan (LPG), a glycolipid abundantly found on the surface of L. donovani promastigotes (the causative agent of visceral leishmaniasis or Kala-azar), resists NET-mediated killing and hinders the expression of the late endosomal markers LAMP1 and RAB7, which inhibits phagosome maturation (the fusion of phagosome with lysosome) by impairing recruitment of the lysosomal marker LAMP1 and protein kinase C-alpha (PKCα) to the phagosome. Here, PRKCA is linked to visceral leishmaniasis.