We upregulated the expression of YBX1 in cells with knockdown of FOXD3-AS1 by transient transfection of over-expressed YBX1 plasmids (Figure 5A) and observed that the proliferation, migration and invasion of NPC cells were activated through CCK8 (Figure 5B), colony formation (Figure 5C), migration (Figure 5D) and transwell (Figure 5E) assays. This evidence concerns the gene YBX1 and nasopharyngeal carcinoma.