Moreover, UPS10 (ubiquitin-specific peptidase 10), a deubiquitinase, promotes proliferation of hepatocellular carcinoma by deubiquitinating and stabilizing YAP/TAZ, and suppresses lung tumorigenesis by deubiquitinating and stabilizing KLF4 (50, 51). Here, USP10 is linked to hepatocellular carcinoma.