HDAC2 and neoplasm: The NuRD complex consists of chromodomain helicase DNA-binding proteins (CHD3/CHD4/CHD5), HDAC1/HDAC2, metastasis associated proteins (MTA1/MTA2/MTA3), methyl domain binding proteins (MBD2/MBD3), retinoblastoma binding proteins (RBBP4/RBBP7), and GATA zinc finger domain proteins (GATAD2B/GATAD2A) (34, 35), and all NuRD components showed high expression in tumour cells (36).