Deletion of YAP/TAZ significantly reduced the ability of KRASG12D mice to induce ADM in response to cerulein, and these mice (KRASG12D;YAP1fl/fl;TAZfl/fl) were free of PanIN lesions at 3 months after the transient induction of pancreatitis by cerulein, similar to control mice (59). The gene discussed is YAP1; the disease is pancreatitis.